WebIn recent studies, we demonstrated that a specific ubiquitination modification of IRF3 triggers RIPA (Chattopadhyay et al., Immunity 2016, Protein Cell 2024). Moreover, in the … WebBackground: Cancer patients present a distinct vulnerability to COVID-19. It is unclear if chemotherapy could accentuate the overall risk in these patients. Methods: We performed a retrospective analysis linking COVID-19 data and oncological information systems to compare lethality in patients undergoing cytotoxic chemotherapy before COVID-19. We …
D. P. Chattopadhyaya - Wikipedia
WebOct 15, 2024 · The discovery of the 427 aa IRF3 (419 aa in mouse) and the understanding of its properties is the basis for the current model for the immediate IFN and ISG expression during viral infections. The details of … [email protected] [Abstract] Interferon regulatory factor 3 (IRF3) is a transcription factor, which is critical for the antiviral response against a wide range of viruses ( Hiscott, 2007; Ikushima et al. , 2013) . ratio\\u0027s vc
PubMed
WebDec 22, 2024 · Chattopadhyay laboratory is interested in studying how the interferon system protects against virus infection. In this context, Dr. Chattopadhyay has been studying how a key transcription factor … WebIRF3 and STAT1 nuclear translocation in HBV-infected HepG2-NTCP. HepG2-NTCP was either mock infected or HBV (400 genomes/cell) infected. ... Asabe S, Wieland SF, Chattopadhyay PK, Roederer M, Engle RE, Purcell RH, Chisari FV. The size of the viral inoculum contributes to the outcome of hepatitis B virus infection. J Virol. WebMar 26, 2024 · In RIPA, IRF3 interacts with BCL-2-Associated X protein (BAX), a pro-apoptotic factor (Chattopadhyay et al., 2010). Upon binding to BAX, IRF3 translocates … ratio\u0027s vc